M183-1337 Screening compound: 2-[4-(3-methylpiperidin-1-yl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-[3-(methylsulfanyl)phenyl]acetamide

M183-1337 Screening compound: 2-[4-(3-methylpiperidin-1-yl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-[3-(methylsulfanyl)phenyl]acetamide
M183-1337 Screening compound: 2-[4-(3-methylpiperidin-1-yl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-[3-(methylsulfanyl)phenyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M183-1337
2-[4-(3-methylpiperidin-1-yl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-[3-(methylsulfanyl)phenyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M183-1337

Molecular Formula

C23H26N4O2S (C23 H26 N4 O2 S)

Compound Name

2-[4-(3-methylpiperidin-1-yl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-[3-(methylsulfanyl)phenyl]acetamide

IUPAC name

2-[4-(3-methylpiperidin-1-yl)-1-oxo-12-dihydrophthalazin-2-yl]-N-[3-(methylsulfanyl)phenyl]acetamide

SMILES

CC(CCC1)CN1C(c1c2cccc1)=NN(CC(Nc1cccc(SC)c1)=O)C2=O

InChI

InChI=1S/C23H26N4O2S/c1-16-7-6-12-26(14-16)22-19-10-3-4-11-20(19)23(29)27(25-22)15-21(28)24-17-8-5-9-18(13-17)30-2/h3-5,8-11,13,16H,6-7,12,14-15H2,1-2H3,(H,24,28)/t16-/m0/s1

InChI Key

UVGNGLHJQGWKHO-INIZCTEOSA-N

MDL Number (MFCD)

MFCD15141290

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.851

Distribution Coefficient, logD

3.851

Water Solubility, LogSw

-3.88

Polar Surface Area

53.320

Acid Dissociation Constant (pKa)

12.95

Base Dissociation Constant (pKb)

0.96

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

34.80

M183-1337 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with M183-1337 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M183-1337?
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What is the minimum amount of M183-1337 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M183-1337
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M183-1337
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M183-1337 available by request