M183-1342 Screening compound: N-(2-chloro-4-fluorophenyl)-2-[4-(3-methylpiperidin-1-yl)-1-oxo-1,2-dihydrophthalazin-2-yl]acetamide

M183-1342 Screening compound: N-(2-chloro-4-fluorophenyl)-2-[4-(3-methylpiperidin-1-yl)-1-oxo-1,2-dihydrophthalazin-2-yl]acetamide
M183-1342 Screening compound: N-(2-chloro-4-fluorophenyl)-2-[4-(3-methylpiperidin-1-yl)-1-oxo-1,2-dihydrophthalazin-2-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M183-1342
N-(2-chloro-4-fluorophenyl)-2-[4-(3-methylpiperidin-1-yl)-1-oxo-1,2-dihydrophthalazin-2-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M183-1342

Molecular Formula

C22H22ClFN4O2 (C22 H22 ClFN4 O2)

Compound Name

N-(2-chloro-4-fluorophenyl)-2-[4-(3-methylpiperidin-1-yl)-1-oxo-1,2-dihydrophthalazin-2-yl]acetamide

IUPAC name

N-(2-chloro-4-fluorophenyl)-2-[4-(3-methylpiperidin-1-yl)-1-oxo-12-dihydrophthalazin-2-yl]acetamide

SMILES

CC(CCC1)CN1C(c1c2cccc1)=NN(CC(Nc(ccc(F)c1)c1Cl)=O)C2=O

InChI

InChI=1S/C22H22ClFN4O2/c1-14-5-4-10-27(12-14)21-16-6-2-3-7-17(16)22(30)28(26-21)13-20(29)25-19-9-8-15(24)11-18(19)23/h2-3,6-9,11,14H,4-5,10,12-13H2,1H3,(H,25,29)/t14-/m0/s1

InChI Key

QXSLDPYHSTWIRE-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD15141295

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.89

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.824

Distribution Coefficient, logD

3.820

Water Solubility, LogSw

-4.16

Polar Surface Area

52.622

Acid Dissociation Constant (pKa)

9.46

Base Dissociation Constant (pKb)

-0.52

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.80

M183-1342 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with M183-1342 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M183-1342?
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What is the minimum amount of M183-1342 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M183-1342
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M183-1342
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M183-1342 available by request