M184-0451 Screening compound: tert-butyl N-(1-{4-amino-5-[4-(propan-2-yl)benzenesulfonyl]pyrimidin-2-yl}piperidin-4-yl)carbamate

M184-0451 Screening compound: tert-butyl N-(1-{4-amino-5-[4-(propan-2-yl)benzenesulfonyl]pyrimidin-2-yl}piperidin-4-yl)carbamate
M184-0451 Screening compound: tert-butyl N-(1-{4-amino-5-[4-(propan-2-yl)benzenesulfonyl]pyrimidin-2-yl}piperidin-4-yl)carbamate alternative view

Chemical Structure Depiction of ChemDiv screening compound M184-0451
tert-butyl N-(1-{4-amino-5-[4-(propan-2-yl)benzenesulfonyl]pyrimidin-2-yl}piperidin-4-yl)carbamate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M184-0451

Molecular Formula

C23H33N5O4S (C23 H33 N5 O4 S)

Compound Name

tert-butyl N-(1-{4-amino-5-[4-(propan-2-yl)benzenesulfonyl]pyrimidin-2-yl}piperidin-4-yl)carbamate

IUPAC name

tert-butyl N-(1-{4-amino-5-[4-(propan-2-yl)benzenesulfonyl]pyrimidin-2-yl}piperidin-4-yl)carbamate

SMILES

CC(C)c(cc1)ccc1S(c1c(N)nc(N(CC2)CCC2NC(OC(C)(C)C)=O)nc1)(=O)=O

InChI

InChI=1S/C23H33N5O4S/c1-15(2)16-6-8-18(9-7-16)33(30,31)19-14-25-21(27-20(19)24)28-12-10-17(11-13-28)26-22(29)32-23(3,4)5/h6-9,14-15,17H,10-13H2,1-5H3,(H,26,29)(H2,24,25,27)

InChI Key

FEYVAKZOVHEMGS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD20751638

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.61

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.395

Distribution Coefficient, logD

4.395

Water Solubility, LogSw

-4.28

Polar Surface Area

103.317

Acid Dissociation Constant (pKa)

16.41

Base Dissociation Constant (pKb)

2.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.20

M184-0451 in Drug Discovery

Included in Screening Libraries

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with M184-0451 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M184-0451?
Check Price and Availability of M184-0451, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M184-0451 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M184-0451
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M184-0451
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M184-0451 available by request