M215-0325 Screening compound: N-(3-fluoro-4-methylphenyl)-1-{3-[(4-methylphenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}piperidine-4-carboxamide

M215-0325 Screening compound: N-(3-fluoro-4-methylphenyl)-1-{3-[(4-methylphenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}piperidine-4-carboxamide
M215-0325 Screening compound: N-(3-fluoro-4-methylphenyl)-1-{3-[(4-methylphenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M215-0325
N-(3-fluoro-4-methylphenyl)-1-{3-[(4-methylphenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M215-0325

Molecular Formula

C27H27FN4O2S (C27 H27 FN4 O2 S)

Compound Name

N-(3-fluoro-4-methylphenyl)-1-{3-[(4-methylphenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}piperidine-4-carboxamide

IUPAC name

N-(3-fluoro-4-methylphenyl)-1-{3-[(4-methylphenyl)methyl]-4-oxo-3H4H-thieno[32-d]pyrimidin-2-yl}piperidine-4-carboxamide

SMILES

Cc1ccc(CN(C2=O)C(N(CC3)CCC3C(Nc3cc(F)c(C)cc3)=O)=Nc3c2scc3)cc1

InChI

InChI=1S/C27H27FN4O2S/c1-17-3-6-19(7-4-17)16-32-26(34)24-23(11-14-35-24)30-27(32)31-12-9-20(10-13-31)25(33)29-21-8-5-18(2)22(28)15-21/h3-8,11,14-15,20H,9-10,12-13,16H2,1-2H3,(H,29,33)

InChI Key

XUQJOHYYHDRDOC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27534386

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.6

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.181

Distribution Coefficient, logD

5.180

Water Solubility, LogSw

-4.98

Polar Surface Area

52.932

Acid Dissociation Constant (pKa)

10.08

Base Dissociation Constant (pKb)

0.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.60

M215-0325 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with M215-0325 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M215-0325?
Check Price and Availability of M215-0325, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M215-0325 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M215-0325
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M215-0325
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M215-0325 available by request