M216-0270 Screening compound: 1-(3-benzyl-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)-N~3~-isobutyl-3-piperidinecarboxamide

M216-0270 Screening compound: 1-(3-benzyl-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)-N~3~-isobutyl-3-piperidinecarboxamide
M216-0270 Screening compound: 1-(3-benzyl-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)-N~3~-isobutyl-3-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M216-0270
1-(3-benzyl-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)-N~3~-isobutyl-3-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M216-0270

Molecular Formula

C23H28N4O2S (C23 H28 N4 O2 S)

Compound Name

1-(3-benzyl-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)-N~3~-isobutyl-3-piperidinecarboxamide

IUPAC name

1-{3-benzyl-4-oxo-3H4H-thieno[32-d]pyrimidin-2-yl}-N-(2-methylpropyl)piperidine-3-carboxamide

SMILES

CC(C)CNC(C(CCC1)CN1C(N(Cc1ccccc1)C1=O)=Nc2c1scc2)=O

InChI

InChI=1S/C23H28N4O2S/c1-16(2)13-24-21(28)18-9-6-11-26(15-18)23-25-19-10-12-30-20(19)22(29)27(23)14-17-7-4-3-5-8-17/h3-5,7-8,10,12,16,18H,6,9,11,13-15H2,1-2H3,(H,24,28)/t18-/m0/s1

InChI Key

FIORGDPKIZFHDT-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27534483

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.691

Distribution Coefficient, logD

3.691

Water Solubility, LogSw

-3.82

Polar Surface Area

54.459

Acid Dissociation Constant (pKa)

15.40

Base Dissociation Constant (pKb)

3.60

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

43.48

M216-0270 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Anti-HIV1 Library (19540 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
Targets:
  • Proteases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M216-0270 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M216-0270?
Check Price and Availability of M216-0270, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M216-0270 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M216-0270
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M216-0270
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M216-0270 available by request