M216-0283 Screening compound: N-[(furan-2-yl)methyl]-1-{3-[(4-methylphenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}piperidine-3-carboxamide

M216-0283 Screening compound: N-[(furan-2-yl)methyl]-1-{3-[(4-methylphenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}piperidine-3-carboxamide
M216-0283 Screening compound: N-[(furan-2-yl)methyl]-1-{3-[(4-methylphenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M216-0283
N-[(furan-2-yl)methyl]-1-{3-[(4-methylphenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M216-0283

Molecular Formula

C25H26N4O3S (C25 H26 N4 O3 S)

Compound Name

N-[(furan-2-yl)methyl]-1-{3-[(4-methylphenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}piperidine-3-carboxamide

IUPAC name

N-[(furan-2-yl)methyl]-1-{3-[(4-methylphenyl)methyl]-4-oxo-3H4H-thieno[32-d]pyrimidin-2-yl}piperidine-3-carboxamide

SMILES

Cc1ccc(CN(C2=O)C(N(CCC3)CC3C(NCc3ccco3)=O)=Nc3c2scc3)cc1

InChI

InChI=1S/C25H26N4O3S/c1-17-6-8-18(9-7-17)15-29-24(31)22-21(10-13-33-22)27-25(29)28-11-2-4-19(16-28)23(30)26-14-20-5-3-12-32-20/h3,5-10,12-13,19H,2,4,11,14-16H2,1H3,(H,26,30)/t19-/m0/s1

InChI Key

VSUQQESHDHHGPT-IBGZPJMESA-N

MDL Number (MFCD)

MFCD27534489

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.954

Distribution Coefficient, logD

3.954

Water Solubility, LogSw

-3.87

Polar Surface Area

61.936

Acid Dissociation Constant (pKa)

12.31

Base Dissociation Constant (pKb)

-1.05

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

32.00

M216-0283 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M216-0283 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M216-0283?
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What is the minimum amount of M216-0283 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M216-0283
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M216-0283
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M216-0283 available by request