M216-0343 Screening compound: 1-{3-[(4-fluorophenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}-N-[2-(thiophen-2-yl)ethyl]piperidine-3-carboxamide

M216-0343 Screening compound: 1-{3-[(4-fluorophenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}-N-[2-(thiophen-2-yl)ethyl]piperidine-3-carboxamide
M216-0343 Screening compound: 1-{3-[(4-fluorophenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}-N-[2-(thiophen-2-yl)ethyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M216-0343
1-{3-[(4-fluorophenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}-N-[2-(thiophen-2-yl)ethyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M216-0343

Molecular Formula

C25H25FN4O2S2 (C25 H25 FN4 O2 S2)

Compound Name

1-{3-[(4-fluorophenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}-N-[2-(thiophen-2-yl)ethyl]piperidine-3-carboxamide

IUPAC name

1-{3-[(4-fluorophenyl)methyl]-4-oxo-3H4H-thieno[32-d]pyrimidin-2-yl}-N-[2-(thiophen-2-yl)ethyl]piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1C(N(Cc(cc1)ccc1F)C1=O)=Nc2c1scc2)NCCc1cccs1

InChI

InChI=1S/C25H25FN4O2S2/c26-19-7-5-17(6-8-19)15-30-24(32)22-21(10-14-34-22)28-25(30)29-12-1-3-18(16-29)23(31)27-11-9-20-4-2-13-33-20/h2,4-8,10,13-14,18H,1,3,9,11-12,15-16H2,(H,27,31)/t18-/m0/s1

InChI Key

JZIXZSGYSPMBNO-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27534537

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.63

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.942

Distribution Coefficient, logD

3.942

Water Solubility, LogSw

-3.94

Polar Surface Area

55.048

Acid Dissociation Constant (pKa)

14.00

Base Dissociation Constant (pKb)

2.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

32.00

M216-0343 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with M216-0343 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M216-0343?
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What is the minimum amount of M216-0343 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M216-0343
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M216-0343
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M216-0343 available by request