M272-1009 Screening compound: 2,5-dimethyl-N-[4-(pyrrolidin-1-yl)quinazolin-7-yl]benzamide

M272-1009 Screening compound: 2,5-dimethyl-N-[4-(pyrrolidin-1-yl)quinazolin-7-yl]benzamide
M272-1009 Screening compound: 2,5-dimethyl-N-[4-(pyrrolidin-1-yl)quinazolin-7-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M272-1009
2,5-dimethyl-N-[4-(pyrrolidin-1-yl)quinazolin-7-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M272-1009

Molecular Formula

C21H22N4O (C21 H22 N4 O)

Compound Name

2,5-dimethyl-N-[4-(pyrrolidin-1-yl)quinazolin-7-yl]benzamide

IUPAC name

25-dimethyl-N-[4-(pyrrolidin-1-yl)quinazolin-7-yl]benzamide

SMILES

Cc1cc(C(Nc2cc3ncnc(N4CCCC4)c3cc2)=O)c(C)cc1

InChI

InChI=1S/C21H22N4O/c1-14-5-6-15(2)18(11-14)21(26)24-16-7-8-17-19(12-16)22-13-23-20(17)25-9-3-4-10-25/h5-8,11-13H,3-4,9-10H2,1-2H3,(H,24,26)

InChI Key

RFSODUDIKRTNRT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27534665

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

346.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.801

Distribution Coefficient, logD

4.647

Water Solubility, LogSw

-4.61

Polar Surface Area

46.606

Acid Dissociation Constant (pKa)

7.78

Base Dissociation Constant (pKb)

5.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

M272-1009 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M272-1009 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M272-1009?
Check Price and Availability of M272-1009, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M272-1009 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M272-1009
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M272-1009
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M272-1009 available by request