M272-1253 Screening compound: 2-chloro-5-(methylsulfanyl)-N-[4-(morpholin-4-yl)quinazolin-7-yl]benzamide

M272-1253 Screening compound: 2-chloro-5-(methylsulfanyl)-N-[4-(morpholin-4-yl)quinazolin-7-yl]benzamide
M272-1253 Screening compound: 2-chloro-5-(methylsulfanyl)-N-[4-(morpholin-4-yl)quinazolin-7-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M272-1253
2-chloro-5-(methylsulfanyl)-N-[4-(morpholin-4-yl)quinazolin-7-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M272-1253

Molecular Formula

C20H19ClN4O2S (C20 H19 ClN4 O2 S)

Compound Name

2-chloro-5-(methylsulfanyl)-N-[4-(morpholin-4-yl)quinazolin-7-yl]benzamide

IUPAC name

2-chloro-5-(methylsulfanyl)-N-[4-(morpholin-4-yl)quinazolin-7-yl]benzamide

SMILES

CSc(cc1)cc(C(Nc2cc3ncnc(N4CCOCC4)c3cc2)=O)c1Cl

InChI

InChI=1S/C20H19ClN4O2S/c1-28-14-3-5-17(21)16(11-14)20(26)24-13-2-4-15-18(10-13)22-12-23-19(15)25-6-8-27-9-7-25/h2-5,10-12H,6-9H2,1H3,(H,24,26)

InChI Key

MCLDCMJPVJNIAR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27534754

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.92

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.377

Distribution Coefficient, logD

4.342

Water Solubility, LogSw

-4.55

Polar Surface Area

54.148

Acid Dissociation Constant (pKa)

8.52

Base Dissociation Constant (pKb)

5.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

M272-1253 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Anticancer Library (62698 compounds)

Antifungal Library (16415 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
  • Nervous system
  • Cardiovascular
Agro:
  • Agro
Targets:
  • Kinases
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with M272-1253 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M272-1253?
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What is the minimum amount of M272-1253 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M272-1253
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M272-1253
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M272-1253 available by request