M274-1134 Screening compound: {3-[2-(4-FLUOROPHENYL)-4-PYRIMIDINYL]PIPERIDINO}(3-FURYL)METHANONE

M274-1134 Screening compound: {3-[2-(4-FLUOROPHENYL)-4-PYRIMIDINYL]PIPERIDINO}(3-FURYL)METHANONE
M274-1134 Screening compound: {3-[2-(4-FLUOROPHENYL)-4-PYRIMIDINYL]PIPERIDINO}(3-FURYL)METHANONE alternative view

Chemical Structure Depiction of ChemDiv screening compound M274-1134
{3-[2-(4-FLUOROPHENYL)-4-PYRIMIDINYL]PIPERIDINO}(3-FURYL)METHANONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M274-1134

Molecular Formula

C20H18FN3O2 (C20 H18 FN3 O2)

Compound Name

{3-[2-(4-FLUOROPHENYL)-4-PYRIMIDINYL]PIPERIDINO}(3-FURYL)METHANONE

IUPAC name

n/a

SMILES

O=C(c1cocc1)N(CCC1)CC1c1ccnc(-c(cc2)ccc2F)n1

InChI

InChI=1S/C20H18FN3O2/c21-17-5-3-14(4-6-17)19-22-9-7-18(23-19)15-2-1-10-24(12-15)20(25)16-8-11-26-13-16/h3-9,11,13,15H,1-2,10,12H2/t15-/m0/s1

InChI Key

GLZLLUUYEHVTGY-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27641733

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.38

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.133

Distribution Coefficient, logD

3.133

Water Solubility, LogSw

-2.99

Polar Surface Area

43.084

Acid Dissociation Constant (pKa)

26.18

Base Dissociation Constant (pKb)

3.60

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.00

M274-1134 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Antibacterial Compounds Library (13827 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Infections
  • Immune system
  • animal
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M274-1134 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M274-1134?
Check Price and Availability of M274-1134, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M274-1134 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M274-1134
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M274-1134
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M274-1134 available by request