M274-1206 Screening compound: 4-[1-(2-fluorobenzoyl)piperidin-3-yl]-2-(4-fluorophenyl)pyrimidine

M274-1206 Screening compound: 4-[1-(2-fluorobenzoyl)piperidin-3-yl]-2-(4-fluorophenyl)pyrimidine
M274-1206 Screening compound: 4-[1-(2-fluorobenzoyl)piperidin-3-yl]-2-(4-fluorophenyl)pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound M274-1206
4-[1-(2-fluorobenzoyl)piperidin-3-yl]-2-(4-fluorophenyl)pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M274-1206

Molecular Formula

C22H19F2N3O (C22 H19 F2 N3 O)

Compound Name

4-[1-(2-fluorobenzoyl)piperidin-3-yl]-2-(4-fluorophenyl)pyrimidine

IUPAC name

4-[1-(2-fluorobenzoyl)piperidin-3-yl]-2-(4-fluorophenyl)pyrimidine

SMILES

O=C(c(cccc1)c1F)N(CCC1)CC1c1nc(-c(cc2)ccc2F)ncc1

InChI

InChI=1S/C22H19F2N3O/c23-17-9-7-15(8-10-17)21-25-12-11-20(26-21)16-4-3-13-27(14-16)22(28)18-5-1-2-6-19(18)24/h1-2,5-12,16H,3-4,13-14H2/t16-/m0/s1

InChI Key

OJAYLEGTVLIFMZ-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27534928

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.41

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.934

Distribution Coefficient, logD

3.934

Water Solubility, LogSw

-4.05

Polar Surface Area

35.280

Acid Dissociation Constant (pKa)

26.18

Base Dissociation Constant (pKb)

3.60

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.73

M274-1206 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with M274-1206 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M274-1206?
Check Price and Availability of M274-1206, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M274-1206 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M274-1206
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M274-1206
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M274-1206 available by request