M276-2626 Screening compound: 2-methyl-3-{4-[(4-methylphenyl)methyl]-2,3-dioxopiperazin-1-yl}-N-[(thiophen-2-yl)methyl]propanamide

M276-2626 Screening compound: 2-methyl-3-{4-[(4-methylphenyl)methyl]-2,3-dioxopiperazin-1-yl}-N-[(thiophen-2-yl)methyl]propanamide
M276-2626 Screening compound: 2-methyl-3-{4-[(4-methylphenyl)methyl]-2,3-dioxopiperazin-1-yl}-N-[(thiophen-2-yl)methyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M276-2626
2-methyl-3-{4-[(4-methylphenyl)methyl]-2,3-dioxopiperazin-1-yl}-N-[(thiophen-2-yl)methyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M276-2626

Molecular Formula

C21H25N3O3S (C21 H25 N3 O3 S)

Compound Name

2-methyl-3-{4-[(4-methylphenyl)methyl]-2,3-dioxopiperazin-1-yl}-N-[(thiophen-2-yl)methyl]propanamide

IUPAC name

2-methyl-3-{4-[(4-methylphenyl)methyl]-23-dioxopiperazin-1-yl}-N-[(thiophen-2-yl)methyl]propanamide

SMILES

CC(CN(CCN(Cc1ccc(C)cc1)C1=O)C1=O)C(NCc1cccs1)=O

InChI

InChI=1S/C21H25N3O3S/c1-15-5-7-17(8-6-15)14-24-10-9-23(20(26)21(24)27)13-16(2)19(25)22-12-18-4-3-11-28-18/h3-8,11,16H,9-10,12-14H2,1-2H3,(H,22,25)/t16-/m0/s1

InChI Key

AIECZIJMDVQPOG-INIZCTEOSA-N

MDL Number (MFCD)

MFCD15141509

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.079

Distribution Coefficient, logD

2.079

Water Solubility, LogSw

-2.63

Polar Surface Area

58.987

Acid Dissociation Constant (pKa)

13.49

Base Dissociation Constant (pKb)

2.11

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.10

M276-2626 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetic Library (37031 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with M276-2626 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M276-2626?
Check Price and Availability of M276-2626, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M276-2626 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M276-2626
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M276-2626
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M276-2626 available by request