M284-0314 Screening compound: 10-[2-(4-isopropylpiperazino)-2-oxoethyl]-7-methyl-2,3-dihydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H,11aH)-dione
Chemical Structure Depiction of ChemDiv screening compound M284-0314
10-[2-(4-isopropylpiperazino)-2-oxoethyl]-7-methyl-2,3-dihydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H,11aH)-dione
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
M284-0314
Molecular Formula
C22H30N4O3 (C22 H30 N4 O3)
Compound Name
10-[2-(4-isopropylpiperazino)-2-oxoethyl]-7-methyl-2,3-dihydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H,11aH)-dione
IUPAC name
13-methyl-9-{2-oxo-2-[4-(propan-2-yl)piperazin-1-yl]ethyl}-39-diazatricyclo[8.4.0.0^{37}]tetradeca-1(14)1012-triene-28-dione
SMILES
CC(C)N(CC1)CCN1C(CN(c(ccc(C)c1)c1C(N1C2CCC1)=O)C2=O)=O
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
398.51
Hydrogen Bond Acceptors Count
7.00
Hydrogen Bond Donors Count
0.00
Rotatable Bond Count
4.00
Number of Nitrogen and Oxygen Atoms
7
Partition Coefficient, logP
0.762
Distribution Coefficient, logD
0.429
Water Solubility, LogSw
-2.14
Polar Surface Area
52.529
Acid Dissociation Constant (pKa)
19.53
Base Dissociation Constant (pKb)
7.46
Number of Chiral Centers
1.00
Percent sp3 carbon bonding
59.09
M284-0314 in Drug Discovery
Included in Screening Libraries
3D-Pharmacophore Based Diversity Library (49813 compounds)
Allosteric Kinases Inhibitors Library (23117 compounds)
300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)
Hsp90-Targeted Library (11355 compounds)
Nonpeptide Peptidomimetics PPI Library (18997 compounds)
Protein-Protein Interaction Library (218420 compounds)
Serine Proteases Inhibitors Library (32732 compounds)
Targeted Diversity Library (40567 compounds)
Beyond the Flatland Library sp3 enriched (92988 compounds)
Epigenetics Focused Set (26518 compounds)
Recognition Elements PPI Library (24135 compounds)
Included in 1.7M Stock Database
- Cancer
- Female
- Congenital
- Skin
- Cancer
- Digestive system
- Respiratory tract
- Male
- Female
- Hemic and lymphatic
- Immune system
- Infections
- Cancer
- Musculoskeletal
- Digestive system
- Respiratory tract
- Male
- Female
- Cardiovascular
- Skin
- Metabolic
- Immune system
- Kinases
- Proteases
- PPI modulators
- PPI modulators
- PPI modulators
- Mimetics
- Cyclic compounds
- Mimetics
References: we are preparing a list of scientific research reports with M284-0314 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)