M284-0331 Screening compound: 7-methyl-10-[2-(4-methylpiperidino)-2-oxoethyl]-2,3-dihydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H,11aH)-dione
Chemical Structure Depiction of ChemDiv screening compound M284-0331
7-methyl-10-[2-(4-methylpiperidino)-2-oxoethyl]-2,3-dihydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H,11aH)-dione
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
M284-0331
Molecular Formula
C21H27N3O3 (C21 H27 N3 O3)
Compound Name
7-methyl-10-[2-(4-methylpiperidino)-2-oxoethyl]-2,3-dihydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H,11aH)-dione
IUPAC name
13-methyl-9-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]-39-diazatricyclo[8.4.0.0^{37}]tetradeca-1(14)1012-triene-28-dione
SMILES
CC(CC1)CCN1C(CN(c(ccc(C)c1)c1C(N1C2CCC1)=O)C2=O)=O
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
369.46
Hydrogen Bond Acceptors Count
6.00
Hydrogen Bond Donors Count
0.00
Rotatable Bond Count
3.00
Number of Nitrogen and Oxygen Atoms
6
Partition Coefficient, logP
1.439
Distribution Coefficient, logD
1.439
Water Solubility, LogSw
-2.24
Polar Surface Area
48.665
Acid Dissociation Constant (pKa)
19.53
Base Dissociation Constant (pKb)
5.13
Number of Chiral Centers
1.00
Percent sp3 carbon bonding
57.14
M284-0331 in Drug Discovery
Included in Screening Libraries
Anticancer Library (62698 compounds)
Antiviral Library (67538 compounds)
300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)
Hsp90-Targeted Library (11355 compounds)
Macl-GPIb alpha Interaction Library (22969 compounds)
Nonpeptide Peptidomimetics PPI Library (18997 compounds)
Protein-Protein Interaction Library (218420 compounds)
Serine Proteases Inhibitors Library (32732 compounds)
Beyond the Flatland Library sp3 enriched (92988 compounds)
Epigenetics Focused Set (26518 compounds)
MDM2-p53 interaction inhibitors Library (21687 compounds)
Recognition Elements PPI Library (24135 compounds)
Included in 1.7M Stock Database
- Cancer
- Antiviral
- Infections
- Immune system
- Cancer
- Digestive system
- Respiratory tract
- Male
- Female
- Hemic and lymphatic
- Immune system
- Hemic and lymphatic
- Cardiovascular
- Infections
- Cancer
- Musculoskeletal
- Digestive system
- Respiratory tract
- Male
- Female
- Cardiovascular
- Skin
- Metabolic
- Immune system
- Cancer
- PPI modulators
- PPI modulators
- PPI modulators
- PPI modulators
- Mimetics
- Cyclic compounds
- Mimetics
- Proteases
References: we are preparing a list of scientific research reports with M284-0331 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)