M286-1313 Screening compound: 3-[(pyrrolidin-1-yl)methyl]-N-[(thiophen-2-yl)methyl]-1H-indole-4-carboxamide

M286-1313 Screening compound: 3-[(pyrrolidin-1-yl)methyl]-N-[(thiophen-2-yl)methyl]-1H-indole-4-carboxamide
M286-1313 Screening compound: 3-[(pyrrolidin-1-yl)methyl]-N-[(thiophen-2-yl)methyl]-1H-indole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M286-1313
3-[(pyrrolidin-1-yl)methyl]-N-[(thiophen-2-yl)methyl]-1H-indole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M286-1313

Molecular Formula

C19H21N3OS (C19 H21 N3 OS)

Compound Name

3-[(pyrrolidin-1-yl)methyl]-N-[(thiophen-2-yl)methyl]-1H-indole-4-carboxamide

IUPAC name

3-[(pyrrolidin-1-yl)methyl]-N-[(thiophen-2-yl)methyl]-1H-indole-4-carboxamide

SMILES

O=C(c1c(c(CN2CCCC2)c[nH]2)c2ccc1)NCc1cccs1

InChI

InChI=1S/C19H21N3OS/c23-19(21-12-15-5-4-10-24-15)16-6-3-7-17-18(16)14(11-20-17)13-22-8-1-2-9-22/h3-7,10-11,20H,1-2,8-9,12-13H2,(H,21,23)

InChI Key

SXFAIMQAVKGMKM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27535139

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

339.46

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.459

Distribution Coefficient, logD

0.573

Water Solubility, LogSw

-3.97

Polar Surface Area

39.639

Acid Dissociation Constant (pKa)

14.18

Base Dissociation Constant (pKb)

10.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

M286-1313 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M286-1313 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M286-1313?
Check Price and Availability of M286-1313, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M286-1313 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M286-1313
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M286-1313
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M286-1313 available by request