M286-1444 Screening compound: [4-(4-methylphenyl)piperazino][3-(1-pyrrolidinylmethyl)-1H-indol-4-yl]methanone

M286-1444 Screening compound: [4-(4-methylphenyl)piperazino][3-(1-pyrrolidinylmethyl)-1H-indol-4-yl]methanone
M286-1444 Screening compound: [4-(4-methylphenyl)piperazino][3-(1-pyrrolidinylmethyl)-1H-indol-4-yl]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound M286-1444
[4-(4-methylphenyl)piperazino][3-(1-pyrrolidinylmethyl)-1H-indol-4-yl]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M286-1444

Molecular Formula

C25H30N4O (C25 H30 N4 O)

Compound Name

[4-(4-methylphenyl)piperazino][3-(1-pyrrolidinylmethyl)-1H-indol-4-yl]methanone

IUPAC name

4-[4-(4-methylphenyl)piperazine-1-carbonyl]-3-[(pyrrolidin-1-yl)methyl]-1H-indole

SMILES

Cc(cc1)ccc1N(CC1)CCN1C(c1c(c(CN2CCCC2)c[nH]2)c2ccc1)=O

InChI

InChI=1S/C25H30N4O/c1-19-7-9-21(10-8-19)28-13-15-29(16-14-28)25(30)22-5-4-6-23-24(22)20(17-26-23)18-27-11-2-3-12-27/h4-10,17,26H,2-3,11-16,18H2,1H3

InChI Key

FFAYSPOOJSMFSG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27535149

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

402.54

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.991

Distribution Coefficient, logD

1.105

Water Solubility, LogSw

-4.32

Polar Surface Area

34.116

Acid Dissociation Constant (pKa)

18.18

Base Dissociation Constant (pKb)

10.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

M286-1444 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Indole Derivatives (10091 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with M286-1444 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M286-1444?
Check Price and Availability of M286-1444, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M286-1444 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M286-1444
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M286-1444
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M286-1444 available by request