M286-1730 Screening compound: N-(3,4-dimethoxyphenyl)-3-[(thiomorpholin-4-yl)methyl]-1H-indole-4-carboxamide

M286-1730 Screening compound: N-(3,4-dimethoxyphenyl)-3-[(thiomorpholin-4-yl)methyl]-1H-indole-4-carboxamide
M286-1730 Screening compound: N-(3,4-dimethoxyphenyl)-3-[(thiomorpholin-4-yl)methyl]-1H-indole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M286-1730
N-(3,4-dimethoxyphenyl)-3-[(thiomorpholin-4-yl)methyl]-1H-indole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M286-1730

Molecular Formula

C22H25N3O3S (C22 H25 N3 O3 S)

Compound Name

N-(3,4-dimethoxyphenyl)-3-[(thiomorpholin-4-yl)methyl]-1H-indole-4-carboxamide

IUPAC name

N-(34-dimethoxyphenyl)-3-[(thiomorpholin-4-yl)methyl]-1H-indole-4-carboxamide

SMILES

COc(ccc(NC(c1c(c(CN2CCSCC2)c[nH]2)c2ccc1)=O)c1)c1OC

InChI

InChI=1S/C22H25N3O3S/c1-27-19-7-6-16(12-20(19)28-2)24-22(26)17-4-3-5-18-21(17)15(13-23-18)14-25-8-10-29-11-9-25/h3-7,12-13,23H,8-11,14H2,1-2H3,(H,24,26)

InChI Key

IJWHKTJDMSVWAC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27642885

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

411.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.053

Distribution Coefficient, logD

2.456

Water Solubility, LogSw

-3.70

Polar Surface Area

52.194

Acid Dissociation Constant (pKa)

11.58

Base Dissociation Constant (pKb)

7.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

M286-1730 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M286-1730 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M286-1730?
Check Price and Availability of M286-1730, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M286-1730 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M286-1730
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M286-1730
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M286-1730 available by request