M286-1740 Screening compound: N-(4-methoxyphenyl)-3-(1,4-thiazinan-4-ylmethyl)-1H-indole-4-carboxamide

M286-1740 Screening compound: N-(4-methoxyphenyl)-3-(1,4-thiazinan-4-ylmethyl)-1H-indole-4-carboxamide
M286-1740 Screening compound: N-(4-methoxyphenyl)-3-(1,4-thiazinan-4-ylmethyl)-1H-indole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M286-1740
N-(4-methoxyphenyl)-3-(1,4-thiazinan-4-ylmethyl)-1H-indole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M286-1740

Molecular Formula

C21H23N3O2S (C21 H23 N3 O2 S)

Compound Name

N-(4-methoxyphenyl)-3-(1,4-thiazinan-4-ylmethyl)-1H-indole-4-carboxamide

IUPAC name

N-(4-methoxyphenyl)-3-[(thiomorpholin-4-yl)methyl]-1H-indole-4-carboxamide

SMILES

COc(cc1)ccc1NC(c1c(c(CN2CCSCC2)c[nH]2)c2ccc1)=O

InChI

InChI=1S/C21H23N3O2S/c1-26-17-7-5-16(6-8-17)23-21(25)18-3-2-4-19-20(18)15(13-22-19)14-24-9-11-27-12-10-24/h2-8,13,22H,9-12,14H2,1H3,(H,23,25)

InChI Key

TUFNQXDGXLDRHO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27535162

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.501

Distribution Coefficient, logD

2.904

Water Solubility, LogSw

-3.96

Polar Surface Area

44.477

Acid Dissociation Constant (pKa)

12.56

Base Dissociation Constant (pKb)

7.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.57

M286-1740 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M286-1740 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M286-1740?
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What is the minimum amount of M286-1740 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M286-1740
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M286-1740
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M286-1740 available by request