M286-1744 Screening compound: N-(4-fluorophenyl)-3-[(thiomorpholin-4-yl)methyl]-1H-indole-4-carboxamide

M286-1744 Screening compound: N-(4-fluorophenyl)-3-[(thiomorpholin-4-yl)methyl]-1H-indole-4-carboxamide
M286-1744 Screening compound: N-(4-fluorophenyl)-3-[(thiomorpholin-4-yl)methyl]-1H-indole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M286-1744
N-(4-fluorophenyl)-3-[(thiomorpholin-4-yl)methyl]-1H-indole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M286-1744

Molecular Formula

C20H20FN3OS (C20 H20 FN3 OS)

Compound Name

N-(4-fluorophenyl)-3-[(thiomorpholin-4-yl)methyl]-1H-indole-4-carboxamide

IUPAC name

N-(4-fluorophenyl)-3-[(thiomorpholin-4-yl)methyl]-1H-indole-4-carboxamide

SMILES

O=C(c1c(c(CN2CCSCC2)c[nH]2)c2ccc1)Nc(cc1)ccc1F

InChI

InChI=1S/C20H20FN3OS/c21-15-4-6-16(7-5-15)23-20(25)17-2-1-3-18-19(17)14(12-22-18)13-24-8-10-26-11-9-24/h1-7,12,22H,8-11,13H2,(H,23,25)

InChI Key

NMAUPIJCTXADPR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27535164

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

369.46

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.547

Distribution Coefficient, logD

2.950

Water Solubility, LogSw

-4.03

Polar Surface Area

36.933

Acid Dissociation Constant (pKa)

11.09

Base Dissociation Constant (pKb)

7.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

M286-1744 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Indole Derivatives (10091 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Structure:
  • Cyclic compounds
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with M286-1744 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M286-1744?
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What is the minimum amount of M286-1744 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M286-1744
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M286-1744
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M286-1744 available by request