M305-2398 Screening compound: 3-{1-[(3-fluorophenyl)sulfonyl]-3-piperidyl}-N~1~-[(5-methyl-1H-pyrazol-4-yl)methyl]propanamide

M305-2398 Screening compound: 3-{1-[(3-fluorophenyl)sulfonyl]-3-piperidyl}-N~1~-[(5-methyl-1H-pyrazol-4-yl)methyl]propanamide
M305-2398 Screening compound: 3-{1-[(3-fluorophenyl)sulfonyl]-3-piperidyl}-N~1~-[(5-methyl-1H-pyrazol-4-yl)methyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M305-2398
3-{1-[(3-fluorophenyl)sulfonyl]-3-piperidyl}-N~1~-[(5-methyl-1H-pyrazol-4-yl)methyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M305-2398

Molecular Formula

C19H25FN4O3S (C19 H25 FN4 O3 S)

Compound Name

3-{1-[(3-fluorophenyl)sulfonyl]-3-piperidyl}-N~1~-[(5-methyl-1H-pyrazol-4-yl)methyl]propanamide

IUPAC name

n/a

SMILES

Cc1c(CNC(CCC(CCC2)CN2S(c2cc(F)ccc2)(=O)=O)=O)cn[nH]1

InChI

InChI=1S/C19H25FN4O3S/c1-14-16(12-22-23-14)11-21-19(25)8-7-15-4-3-9-24(13-15)28(26,27)18-6-2-5-17(20)10-18/h2,5-6,10,12,15H,3-4,7-9,11,13H2,1H3,(H,21,25)(H,22,23)/t15-/m1/s1

InChI Key

LWGPUXQXPQYJRY-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD29017674

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.364

Distribution Coefficient, logD

2.364

Water Solubility, LogSw

-2.75

Polar Surface Area

80.351

Acid Dissociation Constant (pKa)

14.21

Base Dissociation Constant (pKb)

2.05

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

47.40

M305-2398 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M305-2398 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M305-2398?
Check Price and Availability of M305-2398, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M305-2398 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M305-2398
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M305-2398
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M305-2398 available by request