M305-2490 Screening compound: N~1~-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)-3-{1-[(4-fluorophenyl)sulfonyl]-3-piperidyl}propanamide

M305-2490 Screening compound: N~1~-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)-3-{1-[(4-fluorophenyl)sulfonyl]-3-piperidyl}propanamide
M305-2490 Screening compound: N~1~-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)-3-{1-[(4-fluorophenyl)sulfonyl]-3-piperidyl}propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M305-2490
N~1~-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)-3-{1-[(4-fluorophenyl)sulfonyl]-3-piperidyl}propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M305-2490

Molecular Formula

C18H25FN2O5S2 (C18 H25 FN2 O5 S2)

Compound Name

N~1~-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)-3-{1-[(4-fluorophenyl)sulfonyl]-3-piperidyl}propanamide

IUPAC name

N-(11-dioxo-1lambda6-thiolan-3-yl)-3-[1-(4-fluorobenzenesulfonyl)piperidin-3-yl]propanamide

SMILES

O=C(CCC(CCC1)CN1S(c(cc1)ccc1F)(=O)=O)NC(CC1)CS1(=O)=O

InChI

InChI=1S/C18H25FN2O5S2/c19-15-4-6-17(7-5-15)28(25,26)21-10-1-2-14(12-21)3-8-18(22)20-16-9-11-27(23,24)13-16/h4-7,14,16H,1-3,8-13H2,(H,20,22)

InChI Key

QWNOSLUGWPDCFC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29011406

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.54

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.021

Distribution Coefficient, logD

1.021

Water Solubility, LogSw

-2.40

Polar Surface Area

84.245

Acid Dissociation Constant (pKa)

15.74

Base Dissociation Constant (pKb)

-3.02

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

61.10

M305-2490 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

KRAS-Targeted Library (16000 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Hemic and lymphatic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Targets:
  • Kinases
Structure:
  • Mimetics
  • Mimetics
Agro:
  • Agro

References: we are preparing a list of scientific research reports with M305-2490 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M305-2490?
Check Price and Availability of M305-2490, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M305-2490 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M305-2490
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M305-2490
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M305-2490 available by request