M306-0016 Screening compound: 3-[1-(benzenesulfonyl)piperidin-4-yl]-N-[(2-methoxyphenyl)methyl]propanamide

M306-0016 Screening compound: 3-[1-(benzenesulfonyl)piperidin-4-yl]-N-[(2-methoxyphenyl)methyl]propanamide
M306-0016 Screening compound: 3-[1-(benzenesulfonyl)piperidin-4-yl]-N-[(2-methoxyphenyl)methyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M306-0016
3-[1-(benzenesulfonyl)piperidin-4-yl]-N-[(2-methoxyphenyl)methyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M306-0016

Molecular Formula

C22H28N2O4S (C22 H28 N2 O4 S)

Compound Name

3-[1-(benzenesulfonyl)piperidin-4-yl]-N-[(2-methoxyphenyl)methyl]propanamide

IUPAC name

3-[1-(benzenesulfonyl)piperidin-4-yl]-N-[(2-methoxyphenyl)methyl]propanamide

SMILES

COc1c(CNC(CCC(CC2)CCN2S(c2ccccc2)(=O)=O)=O)cccc1

InChI

InChI=1S/C22H28N2O4S/c1-28-21-10-6-5-7-19(21)17-23-22(25)12-11-18-13-15-24(16-14-18)29(26,27)20-8-3-2-4-9-20/h2-10,18H,11-17H2,1H3,(H,23,25)

InChI Key

NVHMZECBJMZZLB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28994101

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.585

Distribution Coefficient, logD

3.585

Water Solubility, LogSw

-3.88

Polar Surface Area

63.780

Acid Dissociation Constant (pKa)

13.01

Base Dissociation Constant (pKb)

-1.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

M306-0016 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

KRAS-Targeted Library (16000 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Targets:
  • Kinases
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M306-0016 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M306-0016?
Check Price and Availability of M306-0016, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M306-0016 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M306-0016
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M306-0016
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M306-0016 available by request