M306-2140 Screening compound: N-(cyclopropylmethyl)-3-[1-(3-fluorobenzenesulfonyl)piperidin-4-yl]-N-propylpropanamide

M306-2140 Screening compound: N-(cyclopropylmethyl)-3-[1-(3-fluorobenzenesulfonyl)piperidin-4-yl]-N-propylpropanamide
M306-2140 Screening compound: N-(cyclopropylmethyl)-3-[1-(3-fluorobenzenesulfonyl)piperidin-4-yl]-N-propylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M306-2140
N-(cyclopropylmethyl)-3-[1-(3-fluorobenzenesulfonyl)piperidin-4-yl]-N-propylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M306-2140

Molecular Formula

C21H31FN2O3S (C21 H31 FN2 O3 S)

Compound Name

N-(cyclopropylmethyl)-3-[1-(3-fluorobenzenesulfonyl)piperidin-4-yl]-N-propylpropanamide

IUPAC name

N-(cyclopropylmethyl)-3-[1-(3-fluorobenzenesulfonyl)piperidin-4-yl]-N-propylpropanamide

SMILES

CCCN(CC1CC1)C(CCC(CC1)CCN1S(c1cc(F)ccc1)(=O)=O)=O

InChI

InChI=1S/C21H31FN2O3S/c1-2-12-23(16-18-6-7-18)21(25)9-8-17-10-13-24(14-11-17)28(26,27)20-5-3-4-19(22)15-20/h3-5,15,17-18H,2,6-14,16H2,1H3

InChI Key

YRNIDRXULSGYDD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31975132

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.55

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.124

Distribution Coefficient, logD

4.124

Water Solubility, LogSw

-4.15

Polar Surface Area

48.135

Acid Dissociation Constant (pKa)

24.49

Base Dissociation Constant (pKb)

2.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

66.67

M306-2140 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M306-2140 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M306-2140?
Check Price and Availability of M306-2140, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M306-2140 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M306-2140
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M306-2140
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M306-2140 available by request