M307-0460 Screening compound: 3-[1-(2-fluorobenzoyl)piperidin-4-yl]-N-{[4-(propan-2-yloxy)phenyl]methyl}propanamide

M307-0460 Screening compound: 3-[1-(2-fluorobenzoyl)piperidin-4-yl]-N-{[4-(propan-2-yloxy)phenyl]methyl}propanamide
M307-0460 Screening compound: 3-[1-(2-fluorobenzoyl)piperidin-4-yl]-N-{[4-(propan-2-yloxy)phenyl]methyl}propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M307-0460
3-[1-(2-fluorobenzoyl)piperidin-4-yl]-N-{[4-(propan-2-yloxy)phenyl]methyl}propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M307-0460

Molecular Formula

C25H31FN2O3 (C25 H31 FN2 O3)

Compound Name

3-[1-(2-fluorobenzoyl)piperidin-4-yl]-N-{[4-(propan-2-yloxy)phenyl]methyl}propanamide

IUPAC name

3-[1-(2-fluorobenzoyl)piperidin-4-yl]-N-{[4-(propan-2-yloxy)phenyl]methyl}propanamide

SMILES

CC(C)Oc1ccc(CNC(CCC(CC2)CCN2C(c(cccc2)c2F)=O)=O)cc1

InChI

InChI=1S/C25H31FN2O3/c1-18(2)31-21-10-7-20(8-11-21)17-27-24(29)12-9-19-13-15-28(16-14-19)25(30)22-5-3-4-6-23(22)26/h3-8,10-11,18-19H,9,12-17H2,1-2H3,(H,27,29)

InChI Key

JRWUVCUQGOAQNK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31992228

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.022

Distribution Coefficient, logD

4.022

Water Solubility, LogSw

-4.29

Polar Surface Area

47.889

Acid Dissociation Constant (pKa)

14.02

Base Dissociation Constant (pKb)

-2.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

M307-0460 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M307-0460 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M307-0460?
Check Price and Availability of M307-0460, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M307-0460 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M307-0460
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M307-0460
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M307-0460 available by request