M307-1089 Screening compound: 3-[1-(4-methylbenzoyl)piperidin-4-yl]-1-[4-(propan-2-yl)piperazin-1-yl]propan-1-one

M307-1089 Screening compound: 3-[1-(4-methylbenzoyl)piperidin-4-yl]-1-[4-(propan-2-yl)piperazin-1-yl]propan-1-one
M307-1089 Screening compound: 3-[1-(4-methylbenzoyl)piperidin-4-yl]-1-[4-(propan-2-yl)piperazin-1-yl]propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M307-1089
3-[1-(4-methylbenzoyl)piperidin-4-yl]-1-[4-(propan-2-yl)piperazin-1-yl]propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M307-1089

Molecular Formula

C23H35N3O2 (C23 H35 N3 O2)

Compound Name

3-[1-(4-methylbenzoyl)piperidin-4-yl]-1-[4-(propan-2-yl)piperazin-1-yl]propan-1-one

IUPAC name

3-[1-(4-methylbenzoyl)piperidin-4-yl]-1-[4-(propan-2-yl)piperazin-1-yl]propan-1-one

SMILES

CC(C)N(CC1)CCN1C(CCC(CC1)CCN1C(c1ccc(C)cc1)=O)=O

InChI

InChI=1S/C23H35N3O2/c1-18(2)24-14-16-25(17-15-24)22(27)9-6-20-10-12-26(13-11-20)23(28)21-7-4-19(3)5-8-21/h4-5,7-8,18,20H,6,9-17H2,1-3H3

InChI Key

QBRMHJBJCQPUDP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31989389

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.55

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.781

Distribution Coefficient, logD

2.235

Water Solubility, LogSw

-3.02

Polar Surface Area

36.872

Acid Dissociation Constant (pKa)

24.49

Base Dissociation Constant (pKb)

7.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

65.22

M307-1089 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M307-1089 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M307-1089?
Check Price and Availability of M307-1089, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M307-1089 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M307-1089
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M307-1089
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M307-1089 available by request