M307-2227 Screening compound: 3-[1-(2-chlorobenzoyl)-4-piperidyl]-N~1~-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)propanamide

M307-2227 Screening compound: 3-[1-(2-chlorobenzoyl)-4-piperidyl]-N~1~-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)propanamide
M307-2227 Screening compound: 3-[1-(2-chlorobenzoyl)-4-piperidyl]-N~1~-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M307-2227
3-[1-(2-chlorobenzoyl)-4-piperidyl]-N~1~-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M307-2227

Molecular Formula

C19H25ClN2O4S (C19 H25 ClN2 O4 S)

Compound Name

3-[1-(2-chlorobenzoyl)-4-piperidyl]-N~1~-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)propanamide

IUPAC name

n/a

SMILES

O=C(CCC(CC1)CCN1C(c(cccc1)c1Cl)=O)NC(CC1)CS1(=O)=O

InChI

InChI=1S/C19H25ClN2O4S/c20-17-4-2-1-3-16(17)19(24)22-10-7-14(8-11-22)5-6-18(23)21-15-9-12-27(25,26)13-15/h1-4,14-15H,5-13H2,(H,21,23)/t15-/m0/s1

InChI Key

JVADHZIDMVGHMH-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD29011614

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.94

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.336

Distribution Coefficient, logD

1.336

Water Solubility, LogSw

-2.96

Polar Surface Area

69.249

Acid Dissociation Constant (pKa)

15.74

Base Dissociation Constant (pKb)

-2.44

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

57.90

M307-2227 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Arginase Targeted Library (2009 compounds)

GPCR Targeted Library (31838 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
  • Mimetics
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Male
  • Cardiovascular
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Others
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
Agro:
  • Agro

References: we are preparing a list of scientific research reports with M307-2227 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M307-2227?
Check Price and Availability of M307-2227, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M307-2227 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M307-2227
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M307-2227
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M307-2227 available by request