M307-2533 Screening compound: N-[2-(3,4-dimethoxyphenyl)ethyl]-3-[1-(2-fluorobenzoyl)piperidin-4-yl]propanamide

M307-2533 Screening compound: N-[2-(3,4-dimethoxyphenyl)ethyl]-3-[1-(2-fluorobenzoyl)piperidin-4-yl]propanamide
M307-2533 Screening compound: N-[2-(3,4-dimethoxyphenyl)ethyl]-3-[1-(2-fluorobenzoyl)piperidin-4-yl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M307-2533
N-[2-(3,4-dimethoxyphenyl)ethyl]-3-[1-(2-fluorobenzoyl)piperidin-4-yl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M307-2533

Molecular Formula

C25H31FN2O4 (C25 H31 FN2 O4)

Compound Name

N-[2-(3,4-dimethoxyphenyl)ethyl]-3-[1-(2-fluorobenzoyl)piperidin-4-yl]propanamide

IUPAC name

N-[2-(34-dimethoxyphenyl)ethyl]-3-[1-(2-fluorobenzoyl)piperidin-4-yl]propanamide

SMILES

COc(ccc(CCNC(CCC(CC1)CCN1C(c(cccc1)c1F)=O)=O)c1)c1OC

InChI

InChI=1S/C25H31FN2O4/c1-31-22-9-7-19(17-23(22)32-2)11-14-27-24(29)10-8-18-12-15-28(16-13-18)25(30)20-5-3-4-6-21(20)26/h3-7,9,17-18H,8,10-16H2,1-2H3,(H,27,29)

InChI Key

RENKWULZAFAYOB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31982876

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.648

Distribution Coefficient, logD

2.648

Water Solubility, LogSw

-3.27

Polar Surface Area

56.189

Acid Dissociation Constant (pKa)

14.38

Base Dissociation Constant (pKb)

-0.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

M307-2533 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M307-2533 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M307-2533?
Check Price and Availability of M307-2533, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M307-2533 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M307-2533
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M307-2533
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M307-2533 available by request