M308-0132 Screening compound: 3-(2-{[(2-chlorophenyl)methyl]carbamoyl}ethyl)-N-(4-methylphenyl)piperidine-1-carboxamide

M308-0132 Screening compound: 3-(2-{[(2-chlorophenyl)methyl]carbamoyl}ethyl)-N-(4-methylphenyl)piperidine-1-carboxamide
M308-0132 Screening compound: 3-(2-{[(2-chlorophenyl)methyl]carbamoyl}ethyl)-N-(4-methylphenyl)piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M308-0132
3-(2-{[(2-chlorophenyl)methyl]carbamoyl}ethyl)-N-(4-methylphenyl)piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M308-0132

Molecular Formula

C23H28ClN3O2 (C23 H28 ClN3 O2)

Compound Name

3-(2-{[(2-chlorophenyl)methyl]carbamoyl}ethyl)-N-(4-methylphenyl)piperidine-1-carboxamide

IUPAC name

3-(2-{[(2-chlorophenyl)methyl]carbamoyl}ethyl)-N-(4-methylphenyl)piperidine-1-carboxamide

SMILES

Cc(cc1)ccc1NC(N1CC(CCC(NCc(cccc2)c2Cl)=O)CCC1)=O

InChI

InChI=1S/C23H28ClN3O2/c1-17-8-11-20(12-9-17)26-23(29)27-14-4-5-18(16-27)10-13-22(28)25-15-19-6-2-3-7-21(19)24/h2-3,6-9,11-12,18H,4-5,10,13-16H2,1H3,(H,25,28)(H,26,29)/t18-/m1/s1

InChI Key

SMLAZCBAHWUPDM-GOSISDBHSA-N

MDL Number (MFCD)

MFCD27535536

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.95

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.738

Distribution Coefficient, logD

4.738

Water Solubility, LogSw

-4.63

Polar Surface Area

49.841

Acid Dissociation Constant (pKa)

13.01

Base Dissociation Constant (pKb)

-0.51

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

39.10

M308-0132 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M308-0132 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M308-0132?
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What is the minimum amount of M308-0132 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M308-0132
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M308-0132
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M308-0132 available by request