M334-0151 Screening compound: N-(1-benzylpiperidin-4-yl)-2-[6-(5-methyl-1,2,4-oxadiazol-3-yl)-2-oxo-3-(propan-2-yl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide

Chemical Structure Depiction of ChemDiv screening compound M334-0151
N-(1-benzylpiperidin-4-yl)-2-[6-(5-methyl-1,2,4-oxadiazol-3-yl)-2-oxo-3-(propan-2-yl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide

Available from 1 mg

Formats:

Glass Vials (4ml Glass Vials VWR #97047-678)
96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Check Price and Availability

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M334-0151

Molecular Formula

C₂₇H₃₂N₆O₃ (C27 H32 N6 O3)

Compound Name

N-(1-benzylpiperidin-4-yl)-2-[6-(5-methyl-1,2,4-oxadiazol-3-yl)-2-oxo-3-(propan-2-yl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide

IUPAC name

N-(1-benzylpiperidin-4-yl)-2-[6-(5-methyl-124-oxadiazol-3-yl)-2-oxo-3-(propan-2-yl)-23-dihydro-1H-13-benzodiazol-1-yl]acetamide

SMILES

CC(C)N(c(ccc(-c1noc(C)n1)c1)c1N1CC(NC2CCN(Cc3ccccc3)CC2)=O)C1=O

InChI

InChI=1S/C27H32N6O3/c1-18(2)33-23-10-9-21(26-28-19(3)36-30-26)15-24(23)32(27(33)35)17-25(34)29-22-11-13-31(14-12-22)16-20-7-5-4-6-8-20/h4-10,15,18,22H,11-14,16-17H2,1-3H3,(H,29,34)

InChI Key

XUXKBWWXYLVJNH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27536932

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

488.59

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

Partition Coefficient, logP

3.646

Distribution Coefficient, logD

2.089

Water Solubility, LogSw

-3.91

Polar Surface Area

76.483

Acid Dissociation Constant (pK_a)

16.47

Base Dissociation Constant (pK_b)

8.95

Number of Chiral Centers

0.00

Percent sp³ carbon bonding

40.70

M334-0151 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Hsp90-Targeted Library (11355 compounds)

PI3K-Targeted Library (17255 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:

Cancer
Female
Congenital
Skin
Nervous system
Cancer
Digestive system
Respiratory tract
Male
Female
Hemic and lymphatic
Immune system
Cancer
Digestive system
Respiratory tract
Otorhinolaryngologic
Male
Female
Hemic and lymphatic
Skin
Cancer
Digestive system
Respiratory tract
Otorhinolaryngologic
Nervous system
Hemic and lymphatic
Cardiovascular

Targets:

Kinases
Kinases
Kinases

Mechanism of action:

PPI modulators
PPI modulators

Structure:

Mimetics
Mimetics

References: we are preparing a list of scientific research reports with M334-0151 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M334-0151?
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What is the minimum amount of M334-0151 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.

Delivery options for M334-0151
ChemDiv sends parcels with Express services (UPS, WC).

1–2 days for small orders
2–4 weeks for large selections

Delivery formats for M334-0151

0.5–50 mg of dry powder sample in single glass vials, custom vials
DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M334-0151 available by request