M334-0163 Screening compound: 3-{2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl}-5-(5-methyl-1,2,4-oxadiazol-3-yl)-1-(propan-2-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one

M334-0163 Screening compound: 3-{2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl}-5-(5-methyl-1,2,4-oxadiazol-3-yl)-1-(propan-2-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one
M334-0163 Screening compound: 3-{2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl}-5-(5-methyl-1,2,4-oxadiazol-3-yl)-1-(propan-2-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M334-0163
3-{2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl}-5-(5-methyl-1,2,4-oxadiazol-3-yl)-1-(propan-2-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M334-0163

Molecular Formula

C24H26N6O5 (C24 H26 N6 O5)

Compound Name

3-{2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl}-5-(5-methyl-1,2,4-oxadiazol-3-yl)-1-(propan-2-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one

IUPAC name

3-{2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl}-5-(5-methyl-124-oxadiazol-3-yl)-1-(propan-2-yl)-23-dihydro-1H-13-benzodiazol-2-one

SMILES

CC(C)N(c(ccc(-c1noc(C)n1)c1)c1N1CC(N(CC2)CCN2C(c2ccco2)=O)=O)C1=O

InChI

InChI=1S/C24H26N6O5/c1-15(2)30-18-7-6-17(22-25-16(3)35-26-22)13-19(18)29(24(30)33)14-21(31)27-8-10-28(11-9-27)23(32)20-5-4-12-34-20/h4-7,12-13,15H,8-11,14H2,1-3H3

InChI Key

MGODYNOQUFKEFD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27536941

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.51

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

2.080

Distribution Coefficient, logD

2.080

Water Solubility, LogSw

-2.70

Polar Surface Area

90.173

Acid Dissociation Constant (pKa)

21.00

Base Dissociation Constant (pKb)

-1.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

M334-0163 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with M334-0163 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M334-0163?
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What is the minimum amount of M334-0163 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M334-0163
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M334-0163
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M334-0163 available by request