M334-0222 Screening compound: N-[1-(furan-2-yl)propan-2-yl]-2-[6-(5-methyl-1,2,4-oxadiazol-3-yl)-2-oxo-3-(propan-2-yl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide

M334-0222 Screening compound: N-[1-(furan-2-yl)propan-2-yl]-2-[6-(5-methyl-1,2,4-oxadiazol-3-yl)-2-oxo-3-(propan-2-yl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide
M334-0222 Screening compound: N-[1-(furan-2-yl)propan-2-yl]-2-[6-(5-methyl-1,2,4-oxadiazol-3-yl)-2-oxo-3-(propan-2-yl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M334-0222
N-[1-(furan-2-yl)propan-2-yl]-2-[6-(5-methyl-1,2,4-oxadiazol-3-yl)-2-oxo-3-(propan-2-yl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M334-0222

Molecular Formula

C22H25N5O4 (C22 H25 N5 O4)

Compound Name

N-[1-(furan-2-yl)propan-2-yl]-2-[6-(5-methyl-1,2,4-oxadiazol-3-yl)-2-oxo-3-(propan-2-yl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide

IUPAC name

N-[1-(furan-2-yl)propan-2-yl]-2-[6-(5-methyl-124-oxadiazol-3-yl)-2-oxo-3-(propan-2-yl)-23-dihydro-1H-13-benzodiazol-1-yl]acetamide

SMILES

CC(C)N(c(ccc(-c1noc(C)n1)c1)c1N1CC(NC(C)Cc2ccco2)=O)C1=O

InChI

InChI=1S/C22H25N5O4/c1-13(2)27-18-8-7-16(21-24-15(4)31-25-21)11-19(18)26(22(27)29)12-20(28)23-14(3)10-17-6-5-9-30-17/h5-9,11,13-14H,10,12H2,1-4H3,(H,23,28)/t14-/m0/s1

InChI Key

DUSBILYIVFJKHM-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD27536965

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.47

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.569

Distribution Coefficient, logD

3.569

Water Solubility, LogSw

-3.85

Polar Surface Area

80.408

Acid Dissociation Constant (pKa)

15.06

Base Dissociation Constant (pKb)

1.72

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.40

M334-0222 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Allosteric Kinases Inhibitors Library (23117 compounds)

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with M334-0222 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M334-0222?
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What is the minimum amount of M334-0222 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M334-0222
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M334-0222
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M334-0222 available by request