M343-0975 Screening compound: N-(5-methylpyridin-2-yl)-2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide

M343-0975 Screening compound: N-(5-methylpyridin-2-yl)-2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide
M343-0975 Screening compound: N-(5-methylpyridin-2-yl)-2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M343-0975
N-(5-methylpyridin-2-yl)-2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M343-0975

Molecular Formula

C22H27N5O4S (C22 H27 N5 O4 S)

Compound Name

N-(5-methylpyridin-2-yl)-2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide

IUPAC name

N-(5-methylpyridin-2-yl)-2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-23-dihydro-1H-13-benzodiazol-1-yl]acetamide

SMILES

CC(C)N(c(ccc(S(N1CCCC1)(=O)=O)c1)c1N1CC(Nc2ncc(C)cc2)=O)C1=O

InChI

InChI=1S/C22H27N5O4S/c1-15(2)27-18-8-7-17(32(30,31)25-10-4-5-11-25)12-19(18)26(22(27)29)14-21(28)24-20-9-6-16(3)13-23-20/h6-9,12-13,15H,4-5,10-11,14H2,1-3H3,(H,23,24,28)

InChI Key

APQASAFPNCRXKE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27537569

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.55

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.555

Distribution Coefficient, logD

3.555

Water Solubility, LogSw

-3.83

Polar Surface Area

82.772

Acid Dissociation Constant (pKa)

10.82

Base Dissociation Constant (pKb)

2.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

M343-0975 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with M343-0975 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M343-0975?
Check Price and Availability of M343-0975, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M343-0975 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M343-0975
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M343-0975
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M343-0975 available by request