M343-0977 Screening compound: 2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]-N-(pyridin-3-yl)acetamide

M343-0977 Screening compound: 2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]-N-(pyridin-3-yl)acetamide
M343-0977 Screening compound: 2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]-N-(pyridin-3-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M343-0977
2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]-N-(pyridin-3-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M343-0977

Molecular Formula

C21H25N5O4S (C21 H25 N5 O4 S)

Compound Name

2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]-N-(pyridin-3-yl)acetamide

IUPAC name

2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-23-dihydro-1H-13-benzodiazol-1-yl]-N-(pyridin-3-yl)acetamide

SMILES

CC(C)N(c(ccc(S(N1CCCC1)(=O)=O)c1)c1N1CC(Nc2cnccc2)=O)C1=O

InChI

InChI=1S/C21H25N5O4S/c1-15(2)26-18-8-7-17(31(29,30)24-10-3-4-11-24)12-19(18)25(21(26)28)14-20(27)23-16-6-5-9-22-13-16/h5-9,12-13,15H,3-4,10-11,14H2,1-2H3,(H,23,27)

InChI Key

WAYVXPRECSQRFE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27537570

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.53

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.526

Distribution Coefficient, logD

2.525

Water Solubility, LogSw

-2.70

Polar Surface Area

82.585

Acid Dissociation Constant (pKa)

12.43

Base Dissociation Constant (pKb)

4.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

M343-0977 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with M343-0977 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M343-0977?
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What is the minimum amount of M343-0977 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M343-0977
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M343-0977
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M343-0977 available by request