M343-1011 Screening compound: N-(2-fluorophenyl)-2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide

M343-1011 Screening compound: N-(2-fluorophenyl)-2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide
M343-1011 Screening compound: N-(2-fluorophenyl)-2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M343-1011
N-(2-fluorophenyl)-2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M343-1011

Molecular Formula

C22H25FN4O4S (C22 H25 FN4 O4 S)

Compound Name

N-(2-fluorophenyl)-2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]acetamide

IUPAC name

N-(2-fluorophenyl)-2-[2-oxo-3-(propan-2-yl)-6-(pyrrolidine-1-sulfonyl)-23-dihydro-1H-13-benzodiazol-1-yl]acetamide

SMILES

CC(C)N(c(ccc(S(N1CCCC1)(=O)=O)c1)c1N1CC(Nc(cccc2)c2F)=O)C1=O

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

460.53

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.383

Distribution Coefficient, logD

3.383

Water Solubility, LogSw

-3.98

Polar Surface Area

72.369

Acid Dissociation Constant (pKa)

10.96

Base Dissociation Constant (pKb)

2.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

M343-1011 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with M343-1011 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M343-1011?
Check Price and Availability of M343-1011, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M343-1011 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M343-1011
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M343-1011
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M343-1011 available by request