M343-1099 Screening compound: 3-(2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-1-(propan-2-yl)-5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one

M343-1099 Screening compound: 3-(2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-1-(propan-2-yl)-5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one
M343-1099 Screening compound: 3-(2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-1-(propan-2-yl)-5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M343-1099
3-(2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-1-(propan-2-yl)-5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M343-1099

Molecular Formula

C23H32N4O6S (C23 H32 N4 O6 S)

Compound Name

3-(2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-1-(propan-2-yl)-5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one

IUPAC name

3-(2-{14-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-1-(propan-2-yl)-5-(pyrrolidine-1-sulfonyl)-23-dihydro-1H-13-benzodiazol-2-one

SMILES

CC(C)N(c(ccc(S(N1CCCC1)(=O)=O)c1)c1N1CC(N(CC2)CCC22OCCO2)=O)C1=O

InChI

InChI=1S/C23H32N4O6S/c1-17(2)27-19-6-5-18(34(30,31)25-9-3-4-10-25)15-20(19)26(22(27)29)16-21(28)24-11-7-23(8-12-24)32-13-14-33-23/h5-6,15,17H,3-4,7-14,16H2,1-2H3

InChI Key

JCLMKPUEPYVMMX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27537622

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

492.6

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.594

Distribution Coefficient, logD

1.594

Water Solubility, LogSw

-2.53

Polar Surface Area

80.747

Acid Dissociation Constant (pKa)

21.85

Base Dissociation Constant (pKb)

1.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

65.20

M343-1099 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M343-1099 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M343-1099?
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What is the minimum amount of M343-1099 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M343-1099
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M343-1099
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M343-1099 available by request