M343-1153 Screening compound: 3-[2-(morpholin-4-yl)-2-oxoethyl]-1-(propan-2-yl)-5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one

M343-1153 Screening compound: 3-[2-(morpholin-4-yl)-2-oxoethyl]-1-(propan-2-yl)-5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one
M343-1153 Screening compound: 3-[2-(morpholin-4-yl)-2-oxoethyl]-1-(propan-2-yl)-5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M343-1153
3-[2-(morpholin-4-yl)-2-oxoethyl]-1-(propan-2-yl)-5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M343-1153

Molecular Formula

C20H28N4O5S (C20 H28 N4 O5 S)

Compound Name

3-[2-(morpholin-4-yl)-2-oxoethyl]-1-(propan-2-yl)-5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one

IUPAC name

3-[2-(morpholin-4-yl)-2-oxoethyl]-1-(propan-2-yl)-5-(pyrrolidine-1-sulfonyl)-23-dihydro-1H-13-benzodiazol-2-one

SMILES

CC(C)N(c(ccc(S(N1CCCC1)(=O)=O)c1)c1N1CC(N2CCOCC2)=O)C1=O

InChI

InChI=1S/C20H28N4O5S/c1-15(2)24-17-6-5-16(30(27,28)22-7-3-4-8-22)13-18(17)23(20(24)26)14-19(25)21-9-11-29-12-10-21/h5-6,13,15H,3-4,7-12,14H2,1-2H3

InChI Key

IYLJTNVBIAKFHE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27537639

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.53

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.373

Distribution Coefficient, logD

1.373

Water Solubility, LogSw

-2.45

Polar Surface Area

74.219

Acid Dissociation Constant (pKa)

21.85

Base Dissociation Constant (pKb)

-0.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.00

M343-1153 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Hsp90-Targeted Library (11355 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M343-1153 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M343-1153?
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What is the minimum amount of M343-1153 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M343-1153
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M343-1153
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M343-1153 available by request