M346-0211 Screening compound: (2E)-3-(2-methoxyphenyl)-N-{4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}prop-2-enamide

M346-0211 Screening compound: (2E)-3-(2-methoxyphenyl)-N-{4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}prop-2-enamide
M346-0211 Screening compound: (2E)-3-(2-methoxyphenyl)-N-{4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}prop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M346-0211
(2E)-3-(2-methoxyphenyl)-N-{4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}prop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M346-0211

Molecular Formula

C19H18N4O2 (C19 H18 N4 O2)

Compound Name

(2E)-3-(2-methoxyphenyl)-N-{4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}prop-2-enamide

IUPAC name

(2E)-3-(2-methoxyphenyl)-N-{4-[(1H-124-triazol-1-yl)methyl]phenyl}prop-2-enamide

SMILES

COc1c(/C=C/C(Nc2ccc(Cn3ncnc3)cc2)=O)cccc1

InChI

InChI=1S/C19H18N4O2/c1-25-18-5-3-2-4-16(18)8-11-19(24)22-17-9-6-15(7-10-17)12-23-14-20-13-21-23/h2-11,13-14H,12H2,1H3,(H,22,24)

InChI Key

GXFJMOZXNNAUON-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27537683

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

334.38

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.658

Distribution Coefficient, logD

2.658

Water Solubility, LogSw

-3.09

Polar Surface Area

55.723

Acid Dissociation Constant (pKa)

12.85

Base Dissociation Constant (pKb)

0.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

M346-0211 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

KRAS-Targeted Library (16000 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with M346-0211 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M346-0211?
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What is the minimum amount of M346-0211 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M346-0211
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M346-0211
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M346-0211 available by request