M346-0254 Screening compound: 2,5-dimethoxy-N-{4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}benzene-1-sulfonamide

M346-0254 Screening compound: 2,5-dimethoxy-N-{4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}benzene-1-sulfonamide
M346-0254 Screening compound: 2,5-dimethoxy-N-{4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M346-0254
2,5-dimethoxy-N-{4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M346-0254

Molecular Formula

C17H18N4O4S (C17 H18 N4 O4 S)

Compound Name

2,5-dimethoxy-N-{4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}benzene-1-sulfonamide

IUPAC name

25-dimethoxy-N-{4-[(1H-124-triazol-1-yl)methyl]phenyl}benzene-1-sulfonamide

SMILES

COc(cc1)cc(S(Nc2ccc(Cn3ncnc3)cc2)(=O)=O)c1OC

InChI

InChI=1S/C17H18N4O4S/c1-24-15-7-8-16(25-2)17(9-15)26(22,23)20-14-5-3-13(4-6-14)10-21-12-18-11-19-21/h3-9,11-12,20H,10H2,1-2H3

InChI Key

DHRIBLSWMGLMSZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27537690

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.42

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.637

Distribution Coefficient, logD

1.630

Water Solubility, LogSw

-2.44

Polar Surface Area

81.039

Acid Dissociation Constant (pKa)

9.19

Base Dissociation Constant (pKb)

1.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.60

M346-0254 in Drug Discovery

Included in Screening Libraries

Immunological Library (6760 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M346-0254 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M346-0254?
Check Price and Availability of M346-0254, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M346-0254 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M346-0254
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M346-0254
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M346-0254 available by request