M346-0285 Screening compound: N-{4-[(1H-1,2,4-TRIAZOL-1-YL)METHYL]PHENYL}-2,3-DIHYDRO-1H-INDENE-5-SULFONAMIDE

M346-0285 Screening compound: N-{4-[(1H-1,2,4-TRIAZOL-1-YL)METHYL]PHENYL}-2,3-DIHYDRO-1H-INDENE-5-SULFONAMIDE
M346-0285 Screening compound: N-{4-[(1H-1,2,4-TRIAZOL-1-YL)METHYL]PHENYL}-2,3-DIHYDRO-1H-INDENE-5-SULFONAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound M346-0285
N-{4-[(1H-1,2,4-TRIAZOL-1-YL)METHYL]PHENYL}-2,3-DIHYDRO-1H-INDENE-5-SULFONAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M346-0285

Molecular Formula

C18H18N4O2S (C18 H18 N4 O2 S)

Compound Name

N-{4-[(1H-1,2,4-TRIAZOL-1-YL)METHYL]PHENYL}-2,3-DIHYDRO-1H-INDENE-5-SULFONAMIDE

IUPAC name

n/a

SMILES

O=S(c1cc(CCC2)c2cc1)(Nc1ccc(Cn2ncnc2)cc1)=O

InChI

InChI=1S/C18H18N4O2S/c23-25(24,18-9-6-15-2-1-3-16(15)10-18)21-17-7-4-14(5-8-17)11-22-13-19-12-20-22/h4-10,12-13,21H,1-3,11H2

InChI Key

VECDIGFPVJIEGN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27537716

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

354.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.654

Distribution Coefficient, logD

2.633

Water Solubility, LogSw

-3.04

Polar Surface Area

66.151

Acid Dissociation Constant (pKa)

8.69

Base Dissociation Constant (pKb)

1.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

M346-0285 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with M346-0285 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M346-0285?
Check Price and Availability of M346-0285, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M346-0285 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M346-0285
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M346-0285
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M346-0285 available by request