M346-0298 Screening compound: 2,4-difluoro-N-{4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}benzene-1-sulfonamide

M346-0298 Screening compound: 2,4-difluoro-N-{4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}benzene-1-sulfonamide
M346-0298 Screening compound: 2,4-difluoro-N-{4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M346-0298
2,4-difluoro-N-{4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M346-0298

Molecular Formula

C15H12F2N4O2S (C15 H12 F2 N4 O2 S)

Compound Name

2,4-difluoro-N-{4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}benzene-1-sulfonamide

IUPAC name

24-difluoro-N-{4-[(1H-124-triazol-1-yl)methyl]phenyl}benzene-1-sulfonamide

SMILES

O=S(c(ccc(F)c1)c1F)(Nc1ccc(Cn2ncnc2)cc1)=O

InChI

InChI=1S/C15H12F2N4O2S/c16-12-3-6-15(14(17)7-12)24(22,23)20-13-4-1-11(2-5-13)8-21-10-18-9-19-21/h1-7,9-10,20H,8H2

InChI Key

KCDFEQKWVIQCOP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11834161

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.35

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.858

Distribution Coefficient, logD

1.802

Water Solubility, LogSw

-2.53

Polar Surface Area

65.865

Acid Dissociation Constant (pKa)

8.27

Base Dissociation Constant (pKb)

1.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.70

M346-0298 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Immune system
  • Digestive system
  • Nervous system
Targets:
  • Nuclear receptors
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M346-0298 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M346-0298?
Check Price and Availability of M346-0298, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M346-0298 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M346-0298
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M346-0298
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M346-0298 available by request