M347-0125 Screening compound: 5-(4-methyl-1,3-thiazol-2-yl)-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-N-[3-(propan-2-yl)phenyl]-1H-pyrrole-3-sulfonamide

M347-0125 Screening compound: 5-(4-methyl-1,3-thiazol-2-yl)-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-N-[3-(propan-2-yl)phenyl]-1H-pyrrole-3-sulfonamide
M347-0125 Screening compound: 5-(4-methyl-1,3-thiazol-2-yl)-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-N-[3-(propan-2-yl)phenyl]-1H-pyrrole-3-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M347-0125
5-(4-methyl-1,3-thiazol-2-yl)-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-N-[3-(propan-2-yl)phenyl]-1H-pyrrole-3-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M347-0125

Molecular Formula

C23H28N4O3S2 (C23 H28 N4 O3 S2)

Compound Name

5-(4-methyl-1,3-thiazol-2-yl)-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-N-[3-(propan-2-yl)phenyl]-1H-pyrrole-3-sulfonamide

IUPAC name

5-(4-methyl-13-thiazol-2-yl)-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-N-[3-(propan-2-yl)phenyl]-1H-pyrrole-3-sulfonamide

SMILES

CC(C)c1cccc(NS(c2cn(CC(N3CCCC3)=O)c(-c3nc(C)cs3)c2)(=O)=O)c1

InChI

InChI=1S/C23H28N4O3S2/c1-16(2)18-7-6-8-19(11-18)25-32(29,30)20-12-21(23-24-17(3)15-31-23)27(13-20)14-22(28)26-9-4-5-10-26/h6-8,11-13,15-16,25H,4-5,9-10,14H2,1-3H3

InChI Key

KXSUPFPQJFCTJD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27537792

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.63

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.223

Distribution Coefficient, logD

4.222

Water Solubility, LogSw

-4.02

Polar Surface Area

68.669

Acid Dissociation Constant (pKa)

10.30

Base Dissociation Constant (pKb)

1.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

M347-0125 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M347-0125 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M347-0125?
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What is the minimum amount of M347-0125 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M347-0125
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M347-0125
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M347-0125 available by request