M347-0405 Screening compound: 5-(4-methyl-1,3-thiazol-2-yl)-1-[2-oxo-2-(piperidin-1-yl)ethyl]-N-[1-(pyridin-3-yl)ethyl]-1H-pyrrole-3-sulfonamide

M347-0405 Screening compound: 5-(4-methyl-1,3-thiazol-2-yl)-1-[2-oxo-2-(piperidin-1-yl)ethyl]-N-[1-(pyridin-3-yl)ethyl]-1H-pyrrole-3-sulfonamide
M347-0405 Screening compound: 5-(4-methyl-1,3-thiazol-2-yl)-1-[2-oxo-2-(piperidin-1-yl)ethyl]-N-[1-(pyridin-3-yl)ethyl]-1H-pyrrole-3-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M347-0405
5-(4-methyl-1,3-thiazol-2-yl)-1-[2-oxo-2-(piperidin-1-yl)ethyl]-N-[1-(pyridin-3-yl)ethyl]-1H-pyrrole-3-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M347-0405

Molecular Formula

C22H27N5O3S2 (C22 H27 N5 O3 S2)

Compound Name

5-(4-methyl-1,3-thiazol-2-yl)-1-[2-oxo-2-(piperidin-1-yl)ethyl]-N-[1-(pyridin-3-yl)ethyl]-1H-pyrrole-3-sulfonamide

IUPAC name

5-(4-methyl-13-thiazol-2-yl)-1-[2-oxo-2-(piperidin-1-yl)ethyl]-N-[1-(pyridin-3-yl)ethyl]-1H-pyrrole-3-sulfonamide

SMILES

CC(c1cnccc1)NS(c1cn(CC(N2CCCCC2)=O)c(-c2nc(C)cs2)c1)(=O)=O

InChI

InChI=1S/C22H27N5O3S2/c1-16-15-31-22(24-16)20-11-19(13-27(20)14-21(28)26-9-4-3-5-10-26)32(29,30)25-17(2)18-7-6-8-23-12-18/h6-8,11-13,15,17,25H,3-5,9-10,14H2,1-2H3/t17-/m0/s1

InChI Key

WTYGMVDWQNPXQE-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27537936

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

473.62

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.276

Distribution Coefficient, logD

2.273

Water Solubility, LogSw

-2.65

Polar Surface Area

78.306

Acid Dissociation Constant (pKa)

9.63

Base Dissociation Constant (pKb)

3.95

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.90

M347-0405 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M347-0405 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M347-0405?
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What is the minimum amount of M347-0405 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M347-0405
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M347-0405
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M347-0405 available by request