M347-0622 Screening compound: N-[(2,5-DIMETHYLPHENYL)METHYL]-5-(4-METHYL-1,3-THIAZOL-2-YL)-1-[2-(MORPHOLIN-4-YL)-2-OXOETHYL]-1H-PYRROLE-3-SULFONAMIDE

M347-0622 Screening compound: N-[(2,5-DIMETHYLPHENYL)METHYL]-5-(4-METHYL-1,3-THIAZOL-2-YL)-1-[2-(MORPHOLIN-4-YL)-2-OXOETHYL]-1H-PYRROLE-3-SULFONAMIDE
M347-0622 Screening compound: N-[(2,5-DIMETHYLPHENYL)METHYL]-5-(4-METHYL-1,3-THIAZOL-2-YL)-1-[2-(MORPHOLIN-4-YL)-2-OXOETHYL]-1H-PYRROLE-3-SULFONAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound M347-0622
N-[(2,5-DIMETHYLPHENYL)METHYL]-5-(4-METHYL-1,3-THIAZOL-2-YL)-1-[2-(MORPHOLIN-4-YL)-2-OXOETHYL]-1H-PYRROLE-3-SULFONAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M347-0622

Molecular Formula

C23H28N4O4S2 (C23 H28 N4 O4 S2)

Compound Name

N-[(2,5-DIMETHYLPHENYL)METHYL]-5-(4-METHYL-1,3-THIAZOL-2-YL)-1-[2-(MORPHOLIN-4-YL)-2-OXOETHYL]-1H-PYRROLE-3-SULFONAMIDE

IUPAC name

n/a

SMILES

Cc1csc(-c2cc(S(NCc3c(C)ccc(C)c3)(=O)=O)cn2CC(N2CCOCC2)=O)n1

InChI

InChI=1S/C23H28N4O4S2/c1-16-4-5-17(2)19(10-16)12-24-33(29,30)20-11-21(23-25-18(3)15-32-23)27(13-20)14-22(28)26-6-8-31-9-7-26/h4-5,10-11,13,15,24H,6-9,12,14H2,1-3H3

InChI Key

NJAYOSKHNIXGAB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27537978

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

488.63

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.156

Distribution Coefficient, logD

3.155

Water Solubility, LogSw

-3.14

Polar Surface Area

77.321

Acid Dissociation Constant (pKa)

9.94

Base Dissociation Constant (pKb)

1.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

M347-0622 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M347-0622 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M347-0622?
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What is the minimum amount of M347-0622 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M347-0622
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M347-0622
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M347-0622 available by request