M348-0545 Screening compound: 1-[6-(4-ethylphenyl)pyridazin-3-yl]-3,5-dimethyl-N-[(thiophen-2-yl)methyl]-1H-pyrazole-4-sulfonamide

M348-0545 Screening compound: 1-[6-(4-ethylphenyl)pyridazin-3-yl]-3,5-dimethyl-N-[(thiophen-2-yl)methyl]-1H-pyrazole-4-sulfonamide
M348-0545 Screening compound: 1-[6-(4-ethylphenyl)pyridazin-3-yl]-3,5-dimethyl-N-[(thiophen-2-yl)methyl]-1H-pyrazole-4-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M348-0545
1-[6-(4-ethylphenyl)pyridazin-3-yl]-3,5-dimethyl-N-[(thiophen-2-yl)methyl]-1H-pyrazole-4-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M348-0545

Molecular Formula

C22H23N5O2S2 (C22 H23 N5 O2 S2)

Compound Name

1-[6-(4-ethylphenyl)pyridazin-3-yl]-3,5-dimethyl-N-[(thiophen-2-yl)methyl]-1H-pyrazole-4-sulfonamide

IUPAC name

1-[6-(4-ethylphenyl)pyridazin-3-yl]-35-dimethyl-N-[(thiophen-2-yl)methyl]-1H-pyrazole-4-sulfonamide

SMILES

CCc(cc1)ccc1-c(cc1)nnc1-n1nc(C)c(S(NCc2cccs2)(=O)=O)c1C

InChI

InChI=1S/C22H23N5O2S2/c1-4-17-7-9-18(10-8-17)20-11-12-21(25-24-20)27-16(3)22(15(2)26-27)31(28,29)23-14-19-6-5-13-30-19/h5-13,23H,4,14H2,1-3H3

InChI Key

QHCOTHVWLNOSFK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27538097

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.59

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.999

Distribution Coefficient, logD

3.750

Water Solubility, LogSw

-3.99

Polar Surface Area

78.368

Acid Dissociation Constant (pKa)

7.65

Base Dissociation Constant (pKb)

6.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

M348-0545 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with M348-0545 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M348-0545?
Check Price and Availability of M348-0545, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M348-0545 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M348-0545
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M348-0545
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M348-0545 available by request