M351-0320 Screening compound: 1-{[5-(2-ethyl-1,3-thiazol-4-yl)-2-methylthiophen-3-yl]sulfonyl}-4-(4-fluorophenyl)piperazine

M351-0320 Screening compound: 1-{[5-(2-ethyl-1,3-thiazol-4-yl)-2-methylthiophen-3-yl]sulfonyl}-4-(4-fluorophenyl)piperazine
M351-0320 Screening compound: 1-{[5-(2-ethyl-1,3-thiazol-4-yl)-2-methylthiophen-3-yl]sulfonyl}-4-(4-fluorophenyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound M351-0320
1-{[5-(2-ethyl-1,3-thiazol-4-yl)-2-methylthiophen-3-yl]sulfonyl}-4-(4-fluorophenyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M351-0320

Molecular Formula

C20H22FN3O2S3 (C20 H22 FN3 O2 S3)

Compound Name

1-{[5-(2-ethyl-1,3-thiazol-4-yl)-2-methylthiophen-3-yl]sulfonyl}-4-(4-fluorophenyl)piperazine

IUPAC name

1-{[5-(2-ethyl-13-thiazol-4-yl)-2-methylthiophen-3-yl]sulfonyl}-4-(4-fluorophenyl)piperazine

SMILES

CCc1nc(-c2cc(S(N(CC3)CCN3c(cc3)ccc3F)(=O)=O)c(C)s2)cs1

InChI

InChI=1S/C20H22FN3O2S3/c1-3-20-22-17(13-27-20)18-12-19(14(2)28-18)29(25,26)24-10-8-23(9-11-24)16-6-4-15(21)5-7-16/h4-7,12-13H,3,8-11H2,1-2H3

InChI Key

KBLSRJFKYJADQI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27538359

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.61

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.048

Distribution Coefficient, logD

5.048

Water Solubility, LogSw

-4.76

Polar Surface Area

46.457

Acid Dissociation Constant (pKa)

27.87

Base Dissociation Constant (pKb)

2.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

M351-0320 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M351-0320 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M351-0320?
Check Price and Availability of M351-0320, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M351-0320 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M351-0320
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M351-0320
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M351-0320 available by request