M358-0087 Screening compound: N,N,3,5-tetramethyl-1-({4-[4-(pyridin-2-yl)piperazine-1-carbonyl]phenyl}methyl)-1H-pyrazole-4-sulfonamide

M358-0087 Screening compound: N,N,3,5-tetramethyl-1-({4-[4-(pyridin-2-yl)piperazine-1-carbonyl]phenyl}methyl)-1H-pyrazole-4-sulfonamide
M358-0087 Screening compound: N,N,3,5-tetramethyl-1-({4-[4-(pyridin-2-yl)piperazine-1-carbonyl]phenyl}methyl)-1H-pyrazole-4-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M358-0087
N,N,3,5-tetramethyl-1-({4-[4-(pyridin-2-yl)piperazine-1-carbonyl]phenyl}methyl)-1H-pyrazole-4-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M358-0087

Molecular Formula

C24H30N6O3S (C24 H30 N6 O3 S)

Compound Name

N,N,3,5-tetramethyl-1-({4-[4-(pyridin-2-yl)piperazine-1-carbonyl]phenyl}methyl)-1H-pyrazole-4-sulfonamide

IUPAC name

NN35-tetramethyl-1-({4-[4-(pyridin-2-yl)piperazine-1-carbonyl]phenyl}methyl)-1H-pyrazole-4-sulfonamide

SMILES

Cc(n(Cc(cc1)ccc1C(N(CC1)CCN1c1ncccc1)=O)nc1C)c1S(N(C)C)(=O)=O

InChI

InChI=1S/C24H30N6O3S/c1-18-23(34(32,33)27(3)4)19(2)30(26-18)17-20-8-10-21(11-9-20)24(31)29-15-13-28(14-16-29)22-7-5-6-12-25-22/h5-12H,13-17H2,1-4H3

InChI Key

PCNGXKKDCPDWPJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27538623

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.61

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.540

Distribution Coefficient, logD

1.531

Water Solubility, LogSw

-2.31

Polar Surface Area

76.604

Acid Dissociation Constant (pKa)

24.69

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

M358-0087 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with M358-0087 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M358-0087?
Check Price and Availability of M358-0087, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M358-0087 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M358-0087
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M358-0087
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M358-0087 available by request