M358-0537 Screening compound: 4-{[3,5-dimethyl-4-(piperidine-1-sulfonyl)-1H-pyrazol-1-yl]methyl}-N-[(4-fluorophenyl)methyl]benzamide

M358-0537 Screening compound: 4-{[3,5-dimethyl-4-(piperidine-1-sulfonyl)-1H-pyrazol-1-yl]methyl}-N-[(4-fluorophenyl)methyl]benzamide
M358-0537 Screening compound: 4-{[3,5-dimethyl-4-(piperidine-1-sulfonyl)-1H-pyrazol-1-yl]methyl}-N-[(4-fluorophenyl)methyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M358-0537
4-{[3,5-dimethyl-4-(piperidine-1-sulfonyl)-1H-pyrazol-1-yl]methyl}-N-[(4-fluorophenyl)methyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M358-0537

Molecular Formula

C25H29FN4O3S (C25 H29 FN4 O3 S)

Compound Name

4-{[3,5-dimethyl-4-(piperidine-1-sulfonyl)-1H-pyrazol-1-yl]methyl}-N-[(4-fluorophenyl)methyl]benzamide

IUPAC name

4-{[35-dimethyl-4-(piperidine-1-sulfonyl)-1H-pyrazol-1-yl]methyl}-N-[(4-fluorophenyl)methyl]benzamide

SMILES

Cc(n(Cc(cc1)ccc1C(NCc(cc1)ccc1F)=O)nc1C)c1S(N1CCCCC1)(=O)=O

InChI

InChI=1S/C25H29FN4O3S/c1-18-24(34(32,33)29-14-4-3-5-15-29)19(2)30(28-18)17-21-6-10-22(11-7-21)25(31)27-16-20-8-12-23(26)13-9-20/h6-13H,3-5,14-17H2,1-2H3,(H,27,31)

InChI Key

DYQYYXUERICJAO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27538701

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484.59

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.636

Distribution Coefficient, logD

2.636

Water Solubility, LogSw

-3.04

Polar Surface Area

70.645

Acid Dissociation Constant (pKa)

11.18

Base Dissociation Constant (pKb)

-0.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.00

M358-0537 in Drug Discovery

Included in Screening Libraries

Lipid Metabolism Library (9174 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Metabolic

References: we are preparing a list of scientific research reports with M358-0537 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M358-0537?
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What is the minimum amount of M358-0537 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M358-0537
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M358-0537
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M358-0537 available by request