M358-0601 Screening compound: N-(cyclopropylmethyl)-4-{[3,5-dimethyl-4-(piperidine-1-sulfonyl)-1H-pyrazol-1-yl]methyl}benzamide

M358-0601 Screening compound: N-(cyclopropylmethyl)-4-{[3,5-dimethyl-4-(piperidine-1-sulfonyl)-1H-pyrazol-1-yl]methyl}benzamide
M358-0601 Screening compound: N-(cyclopropylmethyl)-4-{[3,5-dimethyl-4-(piperidine-1-sulfonyl)-1H-pyrazol-1-yl]methyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M358-0601
N-(cyclopropylmethyl)-4-{[3,5-dimethyl-4-(piperidine-1-sulfonyl)-1H-pyrazol-1-yl]methyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M358-0601

Molecular Formula

C22H30N4O3S (C22 H30 N4 O3 S)

Compound Name

N-(cyclopropylmethyl)-4-{[3,5-dimethyl-4-(piperidine-1-sulfonyl)-1H-pyrazol-1-yl]methyl}benzamide

IUPAC name

N-(cyclopropylmethyl)-4-{[35-dimethyl-4-(piperidine-1-sulfonyl)-1H-pyrazol-1-yl]methyl}benzamide

SMILES

Cc(n(Cc(cc1)ccc1C(NCC1CC1)=O)nc1C)c1S(N1CCCCC1)(=O)=O

InChI

InChI=1S/C22H30N4O3S/c1-16-21(30(28,29)25-12-4-3-5-13-25)17(2)26(24-16)15-19-8-10-20(11-9-19)22(27)23-14-18-6-7-18/h8-11,18H,3-7,12-15H2,1-2H3,(H,23,27)

InChI Key

OSBRDTXCHNTMGJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27538718

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.57

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.938

Distribution Coefficient, logD

1.938

Water Solubility, LogSw

-2.60

Polar Surface Area

71.168

Acid Dissociation Constant (pKa)

14.51

Base Dissociation Constant (pKb)

-0.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

54.50

M358-0601 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M358-0601 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M358-0601?
Check Price and Availability of M358-0601, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M358-0601 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M358-0601
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M358-0601
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M358-0601 available by request