M358-1184 Screening compound: 4-{[4-(azepane-1-sulfonyl)-3,5-dimethyl-1H-pyrazol-1-yl]methyl}-N-cyclopropylbenzamide

M358-1184 Screening compound: 4-{[4-(azepane-1-sulfonyl)-3,5-dimethyl-1H-pyrazol-1-yl]methyl}-N-cyclopropylbenzamide
M358-1184 Screening compound: 4-{[4-(azepane-1-sulfonyl)-3,5-dimethyl-1H-pyrazol-1-yl]methyl}-N-cyclopropylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M358-1184
4-{[4-(azepane-1-sulfonyl)-3,5-dimethyl-1H-pyrazol-1-yl]methyl}-N-cyclopropylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M358-1184

Molecular Formula

C22H30N4O3S (C22 H30 N4 O3 S)

Compound Name

4-{[4-(azepane-1-sulfonyl)-3,5-dimethyl-1H-pyrazol-1-yl]methyl}-N-cyclopropylbenzamide

IUPAC name

4-{[4-(azepane-1-sulfonyl)-35-dimethyl-1H-pyrazol-1-yl]methyl}-N-cyclopropylbenzamide

SMILES

Cc(n(Cc(cc1)ccc1C(NC1CC1)=O)nc1C)c1S(N1CCCCCC1)(=O)=O

InChI

InChI=1S/C22H30N4O3S/c1-16-21(30(28,29)25-13-5-3-4-6-14-25)17(2)26(24-16)15-18-7-9-19(10-8-18)22(27)23-20-11-12-20/h7-10,20H,3-6,11-15H2,1-2H3,(H,23,27)

InChI Key

RGCSDWBCDIOYAP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27538830

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.57

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.049

Distribution Coefficient, logD

2.049

Water Solubility, LogSw

-2.71

Polar Surface Area

71.032

Acid Dissociation Constant (pKa)

12.24

Base Dissociation Constant (pKb)

-0.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

54.50

M358-1184 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M358-1184 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M358-1184?
Check Price and Availability of M358-1184, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M358-1184 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M358-1184
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M358-1184
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M358-1184 available by request