M372-1042 Screening compound: N-(2-chloro-4-methylphenyl)-6-[(dimethylamino)methyl]-2-methyl-4H-thieno[3,2-b]pyrrole-5-carboxamide

M372-1042 Screening compound: N-(2-chloro-4-methylphenyl)-6-[(dimethylamino)methyl]-2-methyl-4H-thieno[3,2-b]pyrrole-5-carboxamide
M372-1042 Screening compound: N-(2-chloro-4-methylphenyl)-6-[(dimethylamino)methyl]-2-methyl-4H-thieno[3,2-b]pyrrole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M372-1042
N-(2-chloro-4-methylphenyl)-6-[(dimethylamino)methyl]-2-methyl-4H-thieno[3,2-b]pyrrole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M372-1042

Molecular Formula

C18H20ClN3OS (C18 H20 ClN3 OS)

Compound Name

N-(2-chloro-4-methylphenyl)-6-[(dimethylamino)methyl]-2-methyl-4H-thieno[3,2-b]pyrrole-5-carboxamide

IUPAC name

N-(2-chloro-4-methylphenyl)-6-[(dimethylamino)methyl]-2-methyl-4H-thieno[32-b]pyrrole-5-carboxamide

SMILES

Cc1cc([nH]c(C(Nc(ccc(C)c2)c2Cl)=O)c2CN(C)C)c2s1

InChI

InChI=1S/C18H20ClN3OS/c1-10-5-6-14(13(19)7-10)21-18(23)16-12(9-22(3)4)17-15(20-16)8-11(2)24-17/h5-8,20H,9H2,1-4H3,(H,21,23)

InChI Key

LNIBWZRLQDFNAC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27539082

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.9

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.290

Distribution Coefficient, logD

0.580

Water Solubility, LogSw

-4.45

Polar Surface Area

37.657

Acid Dissociation Constant (pKa)

9.50

Base Dissociation Constant (pKb)

10.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

M372-1042 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Mechanism of action:
  • Epigenetic
  • PPI modulators
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M372-1042 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M372-1042?
Check Price and Availability of M372-1042, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M372-1042 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M372-1042
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M372-1042
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M372-1042 available by request